All of that and you have still not really said what it means in Romans 8:8 that "Those who are in the flesh cannot please God." I continue to ask the question, "When the unregenerate mother loves her baby or when she nurses her baby, does that not please God?" I have yet to have anyone answer that question positively. I maintain that God indeed is pleased that anyone, saved or not saved, who demonstrates love for others or who does obey Him in anything. Pleasing God is a bit like obeying God. James tells us in John 2:10, "For whosoever shall keep the whole law, and yet offend in one point, he is guilty of all" James continues to explain what he means there in verse 11, "For he who said, "Do not commit adultery," also said, "Do not murder." If you do not commit adultery but do murder, you have become a transgressor of the law".Context is key.
"6 For the mind [f]set on the flesh is death, but the mind [g]set on the Spirit is life and peace, 7 because the mind [h]set on the flesh is hostile toward God; for it does not subject itself to the law of God, for it is not even able to do so, 8 and those who are in the flesh cannot please God."
If you are hostile to God, you cannot please Him. You are hostile. It is impossible to please God.
"Therefore there is now no condemnation at all for those who are in Christ Jesus. 2 For the law of the Spirit of life [a]in Christ Jesus has set you free from the law of sin and of death. 3 For what the Law could not do, weak as it was through the flesh, God did: sending His own Son in the likeness of [c]sinful flesh and as an offering for sin, He condemned sin in the flesh, 4 so that the requirement of the Law might be fulfilled in us who do not walk [d]according to the flesh but [e]according to the Spirit."
The law of death... hmmm... I remember someone saying the Bible never said that. The requirement of the Law is to live a perfect righteous life. If not, you die. It is impossible to live a perfect righteous life, therefore the law is our death. However Jesus did live a perfect righteous life, and as such fulfilled the law where we cannot. However, He died like a common criminal (and was raised again). As such, along with being God, His death became our fulfillment. The death we were to face, He faced. Our sin imputed to Him, as the high priests of old did for the sacrifice of atonement, and His righteousness became our righteousness before God. However, it is only for those who believe. Do note, the Bible doesn't exactly tell us how everyone came or comes to believe. Israel has a day of reckoning coming, after which Jesus Himself will personally save the remnant. (Zechariah) The will look upon Him whom they have pierced, and they recognize Him, and they are broken. All that remain mourn for Him as for an only child, and all that. Then with the fountains of regeneration and forgiveness. FOR ISRAEL, not the Gentiles. This is God's final act in dealing with Israel before the Millennial kingdom begins.
So God is not saying that in committing one sin He will hold your responsible for sins you have not committed. It means that in order to obey God you must obey God perfectly with not a single disobedient act. In committing only a single sin in your entire life means that you have not obeyed God. I believe we can mirror James' statement concerning obeying God's law with a similar statement concerning pleasing God, that is, For whoever pleases God in everything but fails to please Him in one point has not pleased God.
Thus, in Romans it means that if the unregenerate has done only a single thing in his entire life that is displeasing to God, then he cannot please God. That does not mean that God is displeased with everything that the unregenerate does.